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As it is with elephants: Diarrheagenic E. coli in Davidson County, Tennessee

Friday, June 13, 2014,

  • Location: Light Hall • 2215 Garland Avenue • Nashville, TN 37232
  • Room: 512

Pediatric Infectious Diseases Research Conference presents: 

Monique Foster, M.D.

Fellow, Division of Pediatric Infectious Diseases

Department of Pediatrics, Vanderbilt University Medical Center

As it is with elephants: Diarrheagenic E. coli in Davidson County, Tennessee 

Diarrheal diseases account for 1 in 9 child deaths worldwide, making diarrhea the second leading cause of death among children under the age of 5 years. Data regarding the prevalence of various infectious etiologies are based on surveillance studies; however, epidemiological research is biased towards those agents that are most easily detected. Although diarrheagenic E. coli are among the most common etiologic agents of diarrhea, special requests and specific laboratory capabilities are needed before laboratories will pursue them. Information is not available about predominant E. coli pathotypes within different populations or the rate at which highly virulent E. coli lineages emerge. Epidemiological research into the prevalence and occurrence of outbreaks concerns public health systems worldwide. The combination of conventional culture-based methods and molecular techniques facilitate in the mapping of microbial reservoirs that serve as sources for dissemination of new infections. In our study, we have isolated E. coli strains from stools of symptomatic and asymptomatic children and tested them for the known pathotypes of diarrheagenic E. coli. We found that 6% of all samples tested contained a pathogenic E. coli, specifically, DAEC, EAEC, EPEC and STEC.

Friday, June 13, 2014

11:00 a.m. – 12:00 p.m.

512 Light Hall