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VICB Seminar, Ryan Altman, University of Kansas

Thursday, January 31, 2019,

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  • Location: Light Hall • 2215 Garland Avenue • Nashville, TN 37232

The Vanderbilt Institute of Chemical Biology presents Dr. Ryan Altman, University of Kansas: ""Fluorination Strategies for Synthetic Methodology and Medicinal Chemistry"

Key Lecture Points

• New synthetic methods enable access to fluorinated substructures commonly found biological probes and therapeutic candidates
• A Pd-based catalyst system enables an undirected para-selective C–H functionalization reaction from a simple aromatic substrate
• Fluorinated ethers and ethermimetics perturb distribution, metabolism, and pharmacokinetic properties of neurotherapeutics