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VICB Seminar, Bart Decorte: 'Accessing Biologically Relevant Novel Chemical Space via the Architectural Transformation of Natural Products'

Wednesday, October 17, 2018,

Event Image
  • Location: Biological Sciences Building/Medical Research Building (MRB) III • 465 21st Ave S • Nashville, TN 37232
  • Room: 1220

The Vanderbilt Institute of Chemical Biology (VICB) presents Dr. Bart Decorate, Kodib, LLC: "Accessing Biologically Relevant Novel Chemical Space via the Architectural Transformation of Natural Products"

Key Lecture Points

· Natural products and semisynthetic derivatives
continue to have a profound impact on human
health
· Synthetic efforts based on natural products
have primarily focused on improving their
drug-like features while targeting utility in the
same biological space
· A case study in which natural product building
blocks with known biological activity were
architecturally transformed to access
biologically relevant novel chemical space will
be presented