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Neuroscience Brown Bag Series

Thursday, October 04, 2018,

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  • Location: Wilson Hall • 111 21St Ave S • Nashville, TN 37240
  • Room: 316

Kaleb Lowe

Department of Psychology (Schall Lab)

Vanderbilt University

"Nuances in functional neuron types: how do distinct neuron types support behavior?"

The primate brain has a diversity of neurons differing on anatomical, biophysical, and functional terms. How can we identify neuron types, and what contributions do these distinct neuron types provide to enable unitary behavior? In this talk, I will address both questions. We have recently developed a method by which nuanced differences in functional properties of neurons can be revealed (Lowe & Schall, eNeuro, in press). First, I will demonstrate that distinct neuron types can be identified in primate frontal eye field (FEF) with neurons recorded during a basic memory guided saccade task as well as a more complex visual search task. Next, I will describe visual search tasks with experimental manipulations of stimulus-response congruency and perceptual discriminability. Finally, I will describe how a diversity of neuron types in FEF differentially support visual search.  In total, I will show that this novel method provides a method by which the individual components of behavioral control can be identified and how identifying these components provides leverage on understanding the neural mechanisms of that control.