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Cell and Developmental Biology Seminar: Julie Bastarache, MD

Monday, November 20, 2017,

  • Location: 1220 MRB III

CDB Monday Seminar Series

Julie Bastarache, M.D. presents “Cell-free hemoglobin increases microvascular permeability in sepsis”

Monday November 20th at 12:15 pm 

Room 1220 MRB III

Dr. Bastarache is an Assistant Professor in the Department of Pathology Microbiology and Immunology. Primary faculty are particularly encouraged to attend, to evaluate her suitability as a secondary faculty member of CDB.  When I talked with her personally, Dr Bastarache’s research program seemed to align well with the interests of CDB: to understand the pathophysiology of acute respiratory distress syndrome (ARDS) and sepsis and to uncover novel approaches to prevention and treatment of these devastating conditions.

Link to Julie Bastarache’s faculty page

In her talk, “Cell-free hemoglobin increases microvascular permeability in sepsis”, Dr. Bastarache will discuss:

  • Increased permeability of the pulmonary microvascular endothelium causes acute pulmonary edema and lung dysfunction in sepsis-associated ARDS.
  • Mechanisms regulating microvascular permeability are under intense scrutiny, but proximal triggers of the increased permeability are not well understood.
  • Her proposal that cell-free hemoglobin (CFH) released from red blood cells into the circulation during sepsis causes endothelial apoptosis, and increased permeability.