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VICB Seminar, Robert Garbaccio, Merck, 'An Antibody-Drug Conjugate Approach to Tissue-Selective Glucocorticoids'

Wednesday, November 15, 2017,
  • Location: Biological Sciences Building/Medical Research Building (MRB) III • 465 21st Ave S • Nashville, TN 37232
  • Room: 1220

  The Vanderbilt Institute of Chemical Biology (VICB) presents Dr. Robert Garbaccio, Merck: "An Antibody-Drug Conjugate Approach to Tissue-Selective Glucocorticoids"

Key Lecture Points
·Modality agnostic drug discovery means bringing the best modality to a given biological target
· Peptide, oligonucleotide and bioconjugate modalities realizing increasing clinical success and address complex biology
· Organic and medicinal chemists have an important role to play in the discovery and optimization of these alternative modalities
· The targeted delivery of glucocorticoids to immune cells represents an exciting challenge for chemists to develop novel linker and payload strategies