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VICB Seminar, Ryan Altman, 'Decarboxylative Fluoroalkylation and Fluorinated Peptidomimetic Biological Probes'

Wednesday, November 01, 2017,
  • Location: Biological Sciences Building/Medical Research Building (MRB) III • 465 21st Ave S • Nashville, TN 37232
  • Room: 1220

  The Vanderbilt Institute of Chemical Biology (VICB) presents Dr. Ryan Altman, University of Kansas: "Decarboxylative Fluoroalkylation and Fluorinated Peptidomimetic Biological Probes"

Research Summary:
· New synthetic methods allow access to fluorinated substructures for medicinal chemistry and chemical biology.
· Fluoroalkenes have unique physicochemical properties that can be exploited for synthetic and medicinal chemistry.
· Fluorinated peptidomimetics stabilize and improve blood-brain-barrier permeability of endogenous neuropeptides.

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