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VICB Seminar, Borden Lacy, Vanderbilt University: 'Structures and Functions of the Clostridium Difficile Toxins TcdA and TcdB'

Wednesday, October 11, 2017,
  • Location: Biological Sciences Building/Medical Research Building (MRB) III • 465 21st Ave S • Nashville, TN 37232
  • Room: 1220

  The Vanderbilt Institute of Chemical Biology (VICB) presents Dr. Borden Lacy, Vanderbilt University: "Structures and Functions of the Clostridium Difficile Toxins TcdA and TcdB"

Key Lecture Points
· TcdA and TcdB toxins cause cell intoxication and the clinical manifestations of Clostridium difficile infection.
· The TcdA and TcdB toxins and the pathways they hijack within the host represent targets for therapeutic intervention.
· The structures and mechanisms of action for 4 neutralizing antibodies will be presented.