- Location: 512 Light Hall • 2215 Garland Ave • Nashville, TN 37232
- Room: 512
- Contact: Stephen Doster
- Email: firstname.lastname@example.org
- Phone: 936-3883
- Website: https://medschool.vanderbilt.edu/basic-sciences/discovery-sciences-emerging-scholars-lectures/
The Discovery Sciences Emerging Scholars Lectures series presents Dr. Timothy Downing, UC-Irvine: “Synthetic Genome Regulation for Cell and Tissue Engineering"
The Downing Lab is interested in understanding how the chemical and biophysical microenvironment influences adult cell behavior and phenotype through epigenetic gene regulatory mechanisms. We hope to use this information in the design of next-generation biomaterials. This presentation will describe how specific cues (e.g., topography and matrix stiffness) within cellular microenvironments can influence epigenetic state and facilitate the reprogramming of somatic cells back to pluripotency.